Cerebrovascular disease (stroke) is a leading cause of long-term disability and premature death in people ages 45-64, according to the Centers for Disease Control and Prevention. The CDC released data in August measuring the stroke death rate among people ages 45-64 over two decades.

After declines between 2002 and 2012, stroke death rates among men and women ages 45-64 increased starting around 2013 and continued to increase through 2020 for men and 2021 for women.

The stroke death rate for all adults ages 45-64 declined from 23.9 per 100,000 in 2002 to 20.2 per 100,000 in 2012, according to the National Center for Health Statistics. The rate then increased 7% through 2019, and 12% from 2019 to 2021. The rate then declined 2% through 2022.

For men, the stroke death rate declined from 26.9 per 100,000 in 2002 to 23.5 per 100,000 in 2012. The rate then increased 10% through 2019, and 12% from 2019 to 2020. The rate then declined 2% through 2022.

From 2002 to 2013, the stroke death rate for women declined from 21.1 per 100,000 to 16.6 per 100,000 before increasing 7% through 2019 at 17.8 per 100,000. And another increase at 13% from 2019 to 2021.

In 2022, 19,736 men and women ages 45-64 died of a stroke.