Njoku will undergo testing on Monday to determine the extent of the injury, Browns coach Kevin Stefanski said after the defeat.

On the Browns' second drive of the third quarter, Njoku injured his ankle at the end of a 29-yard catch-and-run. He entered the medical tent before exiting and heading into the locker room. The Browns announced Njoku was questionable to return but he never came back into the game.

He finished Sunday with four catches for 44 yards.

Njoku was named to his first Pro Bowl last season after a breakout campaign in which he recorded career-high marks for receptions (81), yards (882) and touchdown catches (6).